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Monitor Carefully (2)diazepam will improve the stage or outcome of midazolam intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism.Lonafarnib may possibly raise the AUC and peak concentration of CYP2C19 substrates. If coadministration unavoidable, watch for adverse reactions and reduce the CYP2C19 substrate dose in accordance with its

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